In-Vitro Anti-Bacterial Activities of Vitex Negundo

Najeeb Ullah, Abdul Jabbar, Muhammad Ibrahim, Usman Ahmed, Rahmatu, Jan, Muhammad Bilal Ahmed, Zaib Ullah

Abstract


Medicinal plants are commonly used for treating of various diseases, among these plants one is vitex negundo. It has antifungal and antibacterial activity. Traditionally, this plant was used in intermittent fever, ulcer, opthalmia, pleurisy etc. The purpose of this study is to evaluate the medicinal value of vitex negundo. The extraction was carried out in ethanol and portioned into five sub-fractions in increasing order of polarity from hexane, chloroform, ethylacetate, n-butanol and water, and all are subjected to antimicrobial study. Eight bacterial strains were used in this study in which the ethyl acetate and butanol sub fractions shows highest activity, chloroform fraction shows less activity while aqueous fraction nearly show no activity against the tested species. This results show that some interesting bioactive secondary metabolites can be purified from the active sub-fraction of ethyl acetate and butanol.

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International Journal of Basic Medical Sciences and Pharmacy (IJBMSP): ISSN: 2049-4963