A Study of Serum Uric Acid and C-Reactive Protein in Acute Myocardial Infarction

Abstract

Acute Myocardial Infarction (AMI or MI) is more commonly known as heart attack, a medical emergency and the leading cause of death for both men and women all over the world. Therefore this study was undertaken to access the role of Serum Uric Acid, C - Reactive protein (CRP) in AMI. The study population contained 66 subjects divided in two groups, 30 age and sex matched healthy controls and 36 patients with AMI (36-77 years). Serum Uric acid, CRP readings were taken on day 1, 3, 5 and at the time of discharge (8±1days) from the onset of symptoms, the results were found to be statistically significant on all the days as compared to control subjects. These patients had a very low HDL level and very high CRP & Uric acid levels when compared to control subjects. CRP & Uric acid shows a definite pattern presentation during AMI. Dyslipidemia, a conventional risk factor of AMI is also associated in this study. The current study is an attempt at better understanding the behavior and response of Uric acid, CRP in AMI patients. Hence, monitoring of these parameters would be beneficial following AMI and is highly recommended to improve patient‟s outcome.