Prevalence, Types and Predictors of Potential Drug-Drug Interactions in an Internal Medicine Ward of The Mardan Medical Complex, Mardan,Kpk, Pakistan
The aim of this study was to determine the prevalence, types and predictors of potential drug-drug interactions (pDDIs). In this retrospective study, medication records of 40 patients were randomly selected from the internal medicine ward and analyzed for pDDIs. A total of 30 interacting drug pairs resulted into 53 pDDIs. Overall 52.50% patients have at least 1 pDDI regardless of the type of severity; 12.50%, 25% and 42.50% patients have at least one major, moderate and minor pDDI. Out of 53 pDDI the basis of severity 58.49%, 26.41% and 15.41% were of minor, moderate and major types respectively; 96.30% were of delayed onset; whereas those with probable and suspected scientific evidences were 37.73% each. pDDIs were more prevalent in the internal medicine ward, majority of which were of minor type of severity. Patients prescribed with more than 7 number of medication were at high risk of occurrence of pDDIs.
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International Journal of Basic Medical Sciences and Pharmacy (IJBMSP): ISSN: 2049-4963